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Logins 2020
In the lost group, average nucleosome occupancy increased after treatment and release of CTCF180 , whereas in the gained group nucleosome occupancy at CTCF180 binding sites did not change following CTCF recruitment . Taken together, these findings indicate that CTCF binding and nucleosome occupancy at its binding site are anti-correlated. Post-translational modifications of chromatin proteins are known to play an important role in differential protein binding in chromatin. Poly(ADP-ribosyl)ati […]