ADP RUN articles

The pathologic accumulation and aggregation of α-synuclein (α-syn) underlies Parkinson’s disease . The molecular mechanisms by which pathologic α-syn causes neurodegeneration in PD are not known. Here, we found that pathologic α-syn activates poly(adenosine 5′-diphosphate–ribose) polymerase-1 (PARP-1), and PAR generation accelerates the formation of pathologic α-syn, resulting in cell death via parthanatos. PARP inhibitors or genetic deletion of PARP-1 prevented pathologic α-syn toxicity […]

Setting up direct deposit for an employee’s final wages tends to be easier than arranging for the employee to pick up his/her final paycheck or mailing it. The time and money spent on printing, mailing, reconciling, and reissuing paper paychecks can add up. Going paperless eliminates the need to hand out paper checks or wait for payroll delivery. As long as you transmit your payroll 2 banking days prior to the paycheck date, direct deposits are made available to the receiving bank as of […]

Adenosine triphosphate is comprised of the molecule adenosine bound to three phosphate groups. Adenosine is a nucleoside consisting of the nitrogenous base adenine and the five-carbon sugar ribose. The three phosphate groups, in order of closest to furthest from the ribose sugar, are labeled alpha, beta, and gamma. Together, these chemical groups constitute an energy powerhouse. The two bonds between the phosphates are equal high-energy bonds that, when broken, release sufficient energy to pow […]

The employer may also conduct an “individualized assessment” for candidates excluded from consideration to determine if the criminal conduct is job related and consistent with business necessity. Prudent employers screen new hires carefully, often conducting a criminal record check – either in-house, or through a third party agency – as part of the hiring process. Turnaround time for the background check’s results can range from one or two days to one or two months, depending […]

Lautenberg continued in his roles as Chairman and CEO until elected to the United States Senate from New Jersey in 1982. The Coronavirus Aid, Relief, and Economic Security Act (H.R. 748, “CARES Act”) was signed into law on March 27, 2020. The CARES Act is the third stimulus bill aimed at providing relief to employers and individuals affected by COVID-19. Below is a high-level summary of the provisions related to small business assistance, tax, retirement, paid leave, unemployment i […]

Visit the WorkMarket Help Center for support specific to the WorkMarket platform. You can manually set the leave balance for employees under the individual employee profile, or by using a ‘Bulk Actions’ update. Then select ‘Bulk Actions’ and choose ‘Add Leave Type’ to choose the appropriate leave type. Depending on how you count it, the federal government has put up about $4 trillion of pandemic-related relief so far, from loans to tax cuts to new spending. […]